Postdoctoral positions are available in Alberto in the Department of Genetics and Development at Columbia University Irving Medical Center. The Ciccia laboratory investigates 1) the molecular mechanisms that maintain genomic stability to suppress cancer development and regulate chemotherapy and immunotherapy responses (Taglialatela A et al, Molecular Cell, 2021; Huang JW et al, Nature Communications, 2020; Joseph SA et al, DNA Repair, 2020; Taglialatela A et al, Molecular Cell, 2017); 2) the function of nucleotide variants in DNA repair genes using innovative base editing screens (Cuella-Martin R et al, Cell, 2021; Hayward SB and Ciccia A, Current Opinion in Genetics and Development, 2021); 3) the interplay between DNA repair and genome editing (Nambiar TS et al, Molecular Cell, 2022; Nambiar TS et al, Nature Communications, 2019); and develops 4) novel methods for precision genome editing (Billon P et al, Cell Reports, 2020; Billon P et al, Molecular Cell, 2017).