Many genes have deeply conserved functions and expression patterns across plant families, implying deep conservation of cis-regulatory control. While gene sequences are easily annotated, deciphering the location and function of the cis-regulatory elements (CREs) controlling when, where, and to what levels genes are expressed remains challenging. Specifically, plant genomes are highly dynamic and algorithms previously developed for animal genomes are not suitable for plants.
If identified, plant CREs can be later used as targets for genomic editing, holding great promise for future crop improvement.
The suggested project will develop a new approach to identify deeply conserved CREs across angiosperms, which will serve as targets for future crop improvement.
The position is currently offered for 1-year with possible extension upon mutual agreement.
Informal enquiries are also welcome.